The Microenvironment Controls CDX2 Homeobox Gene Expression in Colorectal Cancer Cells

The homeobox gene CDX2 plays a major role in development, especially in the gut, and it also acts as a tumor suppressor in the adult colon. Using orthotopic and heterotopic xenografts of human primary colorectal tumor cells and cell lines in nude mice, we addressed the effect of the microenvironment...

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Hlavní autoři: Benahmed, Fairouz, Gross, Isabelle, Guenot, Dominique, Jehan, Frédéric, Martin, Elisabeth, Domon-Dell, Claire, Brabletz, Thomas, Kedinger, Michèle, Freund, Jean-Noël, Duluc, Isabelle
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2007
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851857/
https://ncbi.nlm.nih.gov/pubmed/17255339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060696
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