Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest

Bloom's syndrome is a rare autosomal recessive genetic disorder characterized by chromosomal aberrations, genetic instability, and cancer predisposition, all of which may be the result of abnormal signal transduction during DNA damage recognition. Here, we show that BLM is an intermediate respo...

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Detalhes bibliográficos
Main Authors: Sengupta, Sagar, Robles, Ana I., Linke, Steven P., Sinogeeva, Natasha I., Zhang, Ran, Pedeux, Remy, Ward, Irene M., Celeste, Arkady, Nussenzweig, André, Chen, Junjie, Halazonetis, Thanos D., Harris, Curtis C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172115/
https://ncbi.nlm.nih.gov/pubmed/15364958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200405128
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