Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest

Bloom's syndrome is a rare autosomal recessive genetic disorder characterized by chromosomal aberrations, genetic instability, and cancer predisposition, all of which may be the result of abnormal signal transduction during DNA damage recognition. Here, we show that BLM is an intermediate respo...

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Détails bibliographiques
Auteurs principaux: Sengupta, Sagar, Robles, Ana I., Linke, Steven P., Sinogeeva, Natasha I., Zhang, Ran, Pedeux, Remy, Ward, Irene M., Celeste, Arkady, Nussenzweig, André, Chen, Junjie, Halazonetis, Thanos D., Harris, Curtis C.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2004
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172115/
https://ncbi.nlm.nih.gov/pubmed/15364958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200405128
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