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Inhibition of the anaphase-promoting complex by the Xnf7 ubiquitin ligase
Degradation of specific protein substrates by the anaphase-promoting complex/cyclosome (APC) is critical for mitotic exit. We have identified the protein Xenopus nuclear factor 7 (Xnf7) as a novel APC inhibitor able to regulate the timing of exit from mitosis. Immunodepletion of Xnf7 from Xenopus la...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171901/ https://ncbi.nlm.nih.gov/pubmed/15824132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200411056 |
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