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CDK4 regulation by TNFR1 and JNK is required for NF-κB–mediated epidermal growth control

Nuclear factor κB (NF-κB) mediates homeostatic growth inhibition in the epidermis, and a loss of NF-κB function promotes proliferation and oncogenesis. To identify mechanisms responsible for these effects, we impaired NF-κB action in the epidermis by three different genetic approaches, including con...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhang, Jennifer Y., Tao, Shiying, Kimmel, Robin, Khavari, Paul A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171750/
https://ncbi.nlm.nih.gov/pubmed/15699216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200411060
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