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Both internalization and AIP1 association are required for TNFR2-mediated JNK Signaling
OBJECTIVE: The proinflammtory cytokine tumor necrosis factor (TNF), primarily via TNF receptor 1 (TNFR1), induces NF-κB-dependent cell survival, and JNK and caspase-dependent cell death, regulating vascular endothelial cell (EC) activation and apoptosis. However, signaling by the second receptor, TN...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3421067/ https://ncbi.nlm.nih.gov/pubmed/22743059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.253666 |
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