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X chromosome choice occurs independently of asynchronous replication timing

In mammals, dosage compensation is achieved by X chromosome inactivation in female cells. Xist is required and sufficient for X inactivation, and Xist gene deletions result in completely skewed X inactivation. In this work, we analyzed skewing of X inactivation in mice with an Xist deletion encompas...

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Detalhes bibliográficos
Main Authors: Gribnau, Joost, Luikenhuis, Sandra, Hochedlinger, Konrad, Monkhorst, Kim, Jaenisch, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171734/
https://ncbi.nlm.nih.gov/pubmed/15668296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200405117
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