G protein β interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus

Extracellular stimuli that activate cell surface receptors modulate glucocorticoid actions via as yet unclear mechanisms. Here, we report that the guanine nucleotide-binding protein (G protein)–coupled receptor-activated WD-repeat Gβ interacts with the glucocorticoid receptor (GR), comigrates with i...

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Hlavní autoři: Kino, Tomoshige, Tiulpakov, Anatoly, Ichijo, Takamasa, Chheng, Ly, Kozasa, Tohru, Chrousos, George P.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2005
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171637/
https://ncbi.nlm.nih.gov/pubmed/15955845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200409150
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