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An ECT2–centralspindlin complex regulates the localization and function of RhoA

In anaphase, the spindle dictates the site of contractile ring assembly. Assembly and ingression of the contractile ring involves activation of myosin-II and actin polymerization, which are triggered by the GTPase RhoA. In many cells, the central spindle affects division plane positioning via unknow...

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Bibliografiske detaljer
Main Authors: Yüce, Özlem, Piekny, Alisa, Glotzer, Michael
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171506/
https://ncbi.nlm.nih.gov/pubmed/16103226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200501097
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