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An ECT2–centralspindlin complex regulates the localization and function of RhoA

In anaphase, the spindle dictates the site of contractile ring assembly. Assembly and ingression of the contractile ring involves activation of myosin-II and actin polymerization, which are triggered by the GTPase RhoA. In many cells, the central spindle affects division plane positioning via unknow...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yüce, Özlem, Piekny, Alisa, Glotzer, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171506/
https://ncbi.nlm.nih.gov/pubmed/16103226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200501097
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