Cdc42 and Par6–PKCζ regulate the spatially localized association of Dlg1 and APC to control cell polarization

Cell polarization is essential in a wide range of biological processes such as morphogenesis, asymmetric division, and directed migration. In this study, we show that two tumor suppressor proteins, adenomatous polyposis coli (APC) and Dlg1-SAP97, are required for the polarization of migrating astroc...

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Bibliografiske detaljer
Main Authors: Etienne-Manneville, Sandrine, Manneville, Jean-Baptiste, Nicholls, Sarah, Ferenczi, Michael A., Hall, Alan
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2005
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171429/
https://ncbi.nlm.nih.gov/pubmed/16157700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200412172
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