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Aberrant lysosomal carbohydrate storage accompanies endocytic defects and neurodegeneration in Drosophila benchwarmer

Lysosomal storage is the most common cause of neurodegenerative brain disease in preadulthood. However, the underlying cellular mechanisms that lead to neuronal dysfunction are unknown. Here, we report that loss of Drosophila benchwarmer (bnch), a predicted lysosomal sugar carrier, leads to carbohyd...

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Bibliografski detalji
Glavni autori: Dermaut, Bart, Norga, Koenraad K., Kania, Artur, Verstreken, Patrik, Pan, Hongling, Zhou, Yi, Callaerts, Patrick, Bellen, Hugo J.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171373/
https://ncbi.nlm.nih.gov/pubmed/15998804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200412001
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