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Dynein Is a Transient Kinetochore Component Whose Binding Is Regulated by Microtubule Attachment, Not Tension

Cytoplasmic dynein is the only known kinetochore protein capable of driving chromosome movement toward spindle poles. In grasshopper spermatocytes, dynein immunofluorescence staining is bright at prometaphase kinetochores and dimmer at metaphase kinetochores. We have determined that these difference...

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Detalles Bibliográficos
Main Authors: King, Jennifer M., Hays, Tom S., Nicklas, R. Bruce
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169441/
https://ncbi.nlm.nih.gov/pubmed/11076960
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