Matrix Metalloproteinase 9 and Vascular Endothelial Growth Factor Are Essential for Osteoclast Recruitment into Developing Long Bones

Bone development requires the recruitment of osteoclast precursors from surrounding mesenchyme, thereby allowing the key events of bone growth such as marrow cavity formation, capillary invasion, and matrix remodeling. We demonstrate that mice deficient in gelatinase B/matrix metalloproteinase (MMP)...

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Hauptverfasser: Engsig, Michael T., Chen, Qing-Jun, Vu, Thiennu H., Pedersen, Anne-Cecilie, Therkidsen, Bente, Lund, Leif R., Henriksen, Kim, Lenhard, Thomas, Foged, Niels T., Werb, Zena, Delaissé, Jean-Marie
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2000
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169432/
https://ncbi.nlm.nih.gov/pubmed/11076971
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