Lower GrB+CD62L(high) CD8 T(CM) effector lymphocyte response to influenza virus in older adults is associated with increased CD28(null) CD8 T lymphocytes

Older adults who are at risk of developing influenza illness, have a low level of influenza virus-stimulated cytotoxic T lymphocyte (CTL) activity as measured by an assay of granzyme B (GrB). The purpose of this study was to determine whether aging affected memory CTL populations identified by GrB e...

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Bibliographic Details
Main Authors:	Xie, Dongxu, McElhaney, Janet E.
Format:	Artigo
Language:	Inglês
Published:	2007
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2169430/ https://ncbi.nlm.nih.gov/pubmed/17570460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2007.05.001
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Lower GrB+CD62L(high) CD8 T(CM) effector lymphocyte response to influenza virus in older adults is associated with increased CD28(null) CD8 T lymphocytes

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