Haploinsufficiency of c-Met in cd44(−/−) Mice Identifies a Collaboration of CD44 and c-Met In Vivo

Recent evidence has shown that the activation of receptor tyrosine kinases is not only dependent on binding of their ligands but in addition requires adhesion molecules as coreceptors. We have identified CD44v6 as a coreceptor for c-Met in several tumor and primary cells. The CD44v6 ectodomain is re...

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Bibliographic Details
Main Authors: Matzke, Alexandra, Sargsyan, Vardanush, Holtmann, Bettina, Aramuni, Gayane, Asan, Esther, Sendtner, Michael, Pace, Giuseppina, Howells, Norma, Zhang, Weiqi, Ponta, Helmut, Orian-Rousseau, Véronique
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169422/
https://ncbi.nlm.nih.gov/pubmed/17923692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01355-07
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