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Accurate Homologous Recombination Is a Prominent Double-Strand Break Repair Pathway in Mammalian Chromosomes and Is Modulated by Mismatch Repair Protein Msh2

We designed DNA substrates to study intrachromosomal recombination in mammalian chromosomes. Each substrate contains a thymidine kinase (tk) gene fused to a neomycin resistance (neo) gene. The fusion gene is disrupted by an oligonucleotide containing the 18-bp recognition site for endonuclease I-Sce...

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Detalles Bibliográficos
Autores principales: Smith, Jason A., Bannister, Laura A., Bhattacharjee, Vikram, Wang, Yibin, Waldman, Barbara Criscuolo, Waldman, Alan S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169143/
https://ncbi.nlm.nih.gov/pubmed/17846123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00455-07
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