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The Mre11/Rad50/Nbs1 Complex Limits Adeno-Associated Virus Transduction and Replication

Adeno-associated virus (AAV) is a parvovirus with a small single-stranded DNA genome that relies on cellular replication machinery together with functions supplied by coinfecting helper viruses. The impact of host factors on AAV infection is not well understood. We explored the connection between AA...

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Detalhes bibliográficos
Main Authors: Schwartz, Rachel A., Palacios, Jose Alejandro, Cassell, Geoffrey D., Adam, Sarah, Giacca, Mauro, Weitzman, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169118/
https://ncbi.nlm.nih.gov/pubmed/17898048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01523-07
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