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Cardiac-Myocyte-Specific Excision of the Vinculin Gene Disrupts Cellular Junctions, Causing Sudden Death or Dilated Cardiomyopathy

Vinculin is a ubiquitously expressed multiliganded protein that links the actin cytoskeleton to the cell membrane. In myocytes, it is localized in protein complexes which anchor the contractile apparatus to the sarcolemma. Its function in the myocardium remains poorly understood. Therefore, we devel...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zemljic-Harpf, Alice E., Miller, Joel C., Henderson, Scott A., Wright, Adam T., Manso, Ana Maria, Elsherif, Laila, Dalton, Nancy D., Thor, Andrea K., Perkins, Guy A., McCulloch, Andrew D., Ross, Robert S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169049/
https://ncbi.nlm.nih.gov/pubmed/17785437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00728-07
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