Novel Role for Vinculin in Ventricular Myocyte Mechanics and Dysfunction

Vinculin (Vcl) plays a key structural role in ventricular myocytes that, when disrupted, can lead to contractile dysfunction and dilated cardiomyopathy. To investigate the role of Vcl in myocyte and myocardial function, cardiomyocyte-specific Vcl knockout mice (cVclKO) and littermate control wild-ty...

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Detaylı Bibliyografya
Asıl Yazarlar: Tangney, Jared R., Chuang, Joyce S., Janssen, Matthew S., Krishnamurthy, Adarsh, Liao, Peter, Hoshijima, Masahiko, Wu, Xin, Meininger, Gerald A., Muthuchamy, Mariappan, Zemljic-Harpf, Alice, Ross, Robert S., Frank, Lawrence R., McCulloch, Andrew D., Omens, Jeffrey H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2013
Konular:
Systems Biophysics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617425/
https://ncbi.nlm.nih.gov/pubmed/23561539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.02.021
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