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Cardiac-Myocyte-Specific Excision of the Vinculin Gene Disrupts Cellular Junctions, Causing Sudden Death or Dilated Cardiomyopathy

Vinculin is a ubiquitously expressed multiliganded protein that links the actin cytoskeleton to the cell membrane. In myocytes, it is localized in protein complexes which anchor the contractile apparatus to the sarcolemma. Its function in the myocardium remains poorly understood. Therefore, we devel...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Zemljic-Harpf, Alice E., Miller, Joel C., Henderson, Scott A., Wright, Adam T., Manso, Ana Maria, Elsherif, Laila, Dalton, Nancy D., Thor, Andrea K., Perkins, Guy A., McCulloch, Andrew D., Ross, Robert S.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology (ASM) 2007
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169049/
https://ncbi.nlm.nih.gov/pubmed/17785437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00728-07
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