Phosphorylation of TPL-2 on Serine 400 Is Essential for Lipopolysaccharide Activation of Extracellular Signal-Regulated Kinase in Macrophages

Tumor progression locus 2 (TPL-2) kinase is essential for Toll-like receptor 4 activation of the mitogen-activated protein kinase extracellular signal-regulated kinase (ERK) and for upregulation of the inflammatory cytokine tumor necrosis factor (TNF) in lipopolysaccharide (LPS)-stimulated macrophag...

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Main Authors: Robinson , M. J., Beinke , S., Kouroumalis, A., Tsichlis, P. N., Ley, S. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169048/
https://ncbi.nlm.nih.gov/pubmed/17709378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00301-07
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