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Analysis of the Role of Autophagy in Replication of Herpes Simplex Virus in Cell Culture
The herpes simplex virus type 1 (HSV-1) neurovirulence gene encoding ICP34.5 controls the autophagy pathway. HSV-1 strains lacking ICP34.5 are attenuated in growth and pathogenesis in animal models and in primary cultured cells. While this growth defect has been attributed to the inability of an ICP...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology (ASM)
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2169004/ https://ncbi.nlm.nih.gov/pubmed/17855538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01356-07 |
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