Structure of Adeno-Associated Virus Serotype 8, a Gene Therapy Vector

Adeno-associated viruses (AAVs) are being developed as gene therapy vectors, and their efficacy could be improved by a detailed understanding of their viral capsid structures. AAV serotype 8 (AAV8) shows a significantly greater liver transduction efficiency than those of other serotypes, which has r...

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Bibliografische gegevens
Hoofdauteurs: Nam, Hyun-Joo, Lane, Michael Douglas, Padron, Eric, Gurda, Brittney, McKenna, Robert, Kohlbrenner, Erik, Aslanidi, George, Byrne, Barry, Muzyczka, Nicholas, Zolotukhin, Sergei, Agbandje-McKenna, Mavis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2007
Onderwerpen:
Structure and Assembly
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168965/
https://ncbi.nlm.nih.gov/pubmed/17728238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01304-07
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