Identification of Acetylated, Tetrahalogenated Benzimidazole d-Ribonucleosides with Enhanced Activity against Human Cytomegalovirus

DNA packaging is the key step in viral maturation and involves binding and cleavage of viral DNA containing specific DNA-packaging motifs. This process is mediated by a group of specific enzymes called terminases. We previously demonstrated that the human cytomegalovirus (HCMV) terminase is composed...

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Bibliografiske detaljer
Main Authors: Hwang, Jae-Seon, Kregler, Oliver, Schilf, Rita, Bannert, Norbert, Drach, John C., Townsend, Leroy B., Bogner, Elke
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2007
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168816/
https://ncbi.nlm.nih.gov/pubmed/17728228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01130-07
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