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Computational Prediction and Experimental Verification of the Gene Encoding the NAD(+)/NADP(+)-Dependent Succinate Semialdehyde Dehydrogenase in Escherichia coli

Although NAD(+)-dependent succinate semialdehyde dehydrogenase activity was first described in Escherichia coli more than 25 years ago, the responsible gene has remained elusive so far. As an experimental proof of concept for a gap-filling algorithm for metabolic networks developed earlier, we demon...

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Autores principales: Fuhrer, Tobias, Chen, Lifeng, Sauer, Uwe, Vitkup, Dennis
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168661/
https://ncbi.nlm.nih.gov/pubmed/17873044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01027-07
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