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Streptomyces coelicolor Undergoes Spontaneous Chromosomal End Replacement

We report a previously unobserved form of genetic instability for Streptomyces coelicolor, the replacement of one chromosome end by the other end. These genetic changes occurred spontaneously in both a wild-type strain and strains harboring a foreign transposon. Deleted and duplicated DNA comprises...

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Bibliographic Details
Main Authors: Widenbrant, Elizabeth M., Tsai, Hsiu-Hui, Chen, Carton W., Kao, Camilla M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168631/
https://ncbi.nlm.nih.gov/pubmed/17951388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01049-07
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