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Introduction of the Foreign Transposon Tn4560 in Streptomyces coelicolor Leads to Genetic Instability near the Native Insertion Sequence IS1649

We report an altered pattern of genetic instability for Streptomyces coelicolor when the bacterium harbored a foreign transposon, Tn4560. Deletions, amplifications, and circularizations of the linear 8.7-Mb chromosome occurred more frequently at sites adjacent to native insertion elements, notably I...

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Autori principali: Widenbrant, Elizabeth M., Kao, Camilla M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168616/
https://ncbi.nlm.nih.gov/pubmed/17951387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00983-07
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