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Introduction of the Foreign Transposon Tn4560 in Streptomyces coelicolor Leads to Genetic Instability near the Native Insertion Sequence IS1649

We report an altered pattern of genetic instability for Streptomyces coelicolor when the bacterium harbored a foreign transposon, Tn4560. Deletions, amplifications, and circularizations of the linear 8.7-Mb chromosome occurred more frequently at sites adjacent to native insertion elements, notably I...

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Detalhes bibliográficos
Main Authors: Widenbrant, Elizabeth M., Kao, Camilla M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168616/
https://ncbi.nlm.nih.gov/pubmed/17951387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00983-07
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