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Characterization of the Mycobacterium tuberculosis 4-Diphosphocytidyl-2-C-Methyl-d-Erythritol Synthase: Potential for Drug Development

Mycobacterium tuberculosis utilizes the methylerythritol phosphate (MEP) pathway for biosynthesis of isopentenyl diphosphate and its isomer, dimethylallyl diphosphate, precursors of all isoprenoid compounds. This pathway is of interest as a source of new drug targets, as it is absent from humans and...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Eoh, Hyungjin, Brown, Amanda C., Buetow, Lori, Hunter, William N., Parish, Tanya, Kaur, Devinder, Brennan, Patrick J., Crick, Dean C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168624/
https://ncbi.nlm.nih.gov/pubmed/17921290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00925-07
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