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The Mycobacterium tuberculosis MEP (2C-methyl-D-erythritol 4-phosphate) pathway as a new drug target

Tuberculosis (TB) is still a major public health problem, compounded by the human immunodeficiency virus (HIV)-TB co-infection and recent emergence of multidrug-resistant (MDR) and extensive drug resistant (XDR)-TB. Novel anti-TB drugs are urgently required. In this context, the 2C-methyl-D-erythrit...

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Detalhes bibliográficos
Main Authors: Eoh, Hyungjin, Brennan, Patrick J., Crick, Dean C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646905/
https://ncbi.nlm.nih.gov/pubmed/18793870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2008.07.004
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