Identification of Francisella tularensis Himar1-Based Transposon Mutants Defective for Replication in Macrophages

Francisella tularensis, the etiologic agent of tularemia in humans, is a potential biological threat due to its low infectious dose and multiple routes of entry. F. tularensis replicates within several cell types, eventually causing cell death by inducing apoptosis. In this study, a modified Himar1...

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Detalhes bibliográficos
Main Authors: Maier, Tamara M., Casey, Monika S., Becker, Rachel H., Dorsey, Caleb W., Glass, Elizabeth M., Maltsev, Natalia, Zahrt, Thomas C., Frank, Dara W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168294/
https://ncbi.nlm.nih.gov/pubmed/17682043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00238-07
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