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Francisella tularensis ΔpyrF Mutants Show that Replication in Nonmacrophages Is Sufficient for Pathogenesis In Vivo

The pathogenesis of Francisella tularensis has been associated with this bacterium's ability to replicate within macrophages. F. tularensis can also invade and replicate in a variety of nonphagocytic host cells, including lung and kidney epithelial cells and hepatocytes. As uracil biosynthesis...

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Detalhes bibliográficos
Main Authors: Horzempa, Joseph, O'Dee, Dawn M., Shanks, Robert M. Q., Nau, Gerard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876533/
https://ncbi.nlm.nih.gov/pubmed/20385757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00134-10
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