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Identification of transposon insertion mutants of Francisella tularensis tularensis strain Schu S4 deficient in intracellular replication in the hepatic cell line HepG2

BACKGROUND: Francisella tularensis is a zoonotic intracellular bacterial pathogen that causes tularemia. The subspecies tularensis is highly virulent and is classified as a category A agent of biological warfare because of its low infectious dose by an aerosol route, and its ability to cause severe...

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Detalhes bibliográficos
Main Authors: Qin, Aiping, Mann, Barbara J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557513/
https://ncbi.nlm.nih.gov/pubmed/16879747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-6-69
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