A Substituted Tetrahydro-Tetrazolo-Pyrimidine Is a Specific and Novel Inhibitor of Hepatitis B Virus Surface Antigen Secretion

The high levels of hepatitis B virus (HBV) surface antigen (HBsAg)-bearing subviral particles in the serum of chronically infected individuals are thought to play a role in suppressing the HBV-specific immune response. Current therapeutics are not directed at reducing this viral antigenemia; thus, o...

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Bibliographic Details
Main Authors: Dougherty, Anne Marie, Guo, Haitao, Westby, Gael, Liu, Yuanjie, Simsek, Ender, Guo, Ju-Tao, Mehta, Anand, Norton, Pamela, Gu, Baohua, Block, Timothy, Cuconati, Andrea
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2007
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2167973/
https://ncbi.nlm.nih.gov/pubmed/17875990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00541-07
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