Drug concentration heterogeneity facilitates the evolution of drug resistance
Pathogenic microorganisms use Darwinian processes to circumvent attempts at their control through chemotherapy. In the case of HIV-1 infection, in which drug resistance is a continuing problem, we show that in one-compartment systems, there is a relatively narrow window of drug concentrations that a...
Сохранить в:
| Опубликовано в:: | Proc Natl Acad Sci U S A |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1998
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21672/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9751697/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.20.11514 |
| Метки: |
Нет меток, Требуется 1-ая метка записи!
|