Aphidicolin inhibits growth and DNA synthesis in halophilic arachaebacteria.

Aphidicolin, a specific inhibitor of eucaryotic alpha DNA polymerase, inhibits the growth of halophilic arachaebacteria. In Halobacterium halobium, aphidicolin prevents cell division and DNA synthesis. These results suggest that arachaebacterial replicases are of the eucaryotic type.

Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Forterre, P, Elie, C, Kohiyama, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1984
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC215722/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6204969/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.159.2.800-802.1984
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