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Aphidicolin inhibits growth and DNA synthesis in halophilic arachaebacteria.

Aphidicolin, a specific inhibitor of eucaryotic alpha DNA polymerase, inhibits the growth of halophilic arachaebacteria. In Halobacterium halobium, aphidicolin prevents cell division and DNA synthesis. These results suggest that arachaebacterial replicases are of the eucaryotic type.

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Détails bibliographiques
Publié dans:J Bacteriol
Auteurs principaux: Forterre, P, Elie, C, Kohiyama, M
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1984
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC215722/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6204969/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.159.2.800-802.1984
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