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Three-Dimensional Location of the Imperatoxin a Binding Site on the Ryanodine Receptor

Cryo-electron microscopy and three-dimensional, single-particle image analysis have been used to reveal the specific binding site of imperatoxin A (IpTx(a)) on the architecture of the calcium release channel/ryanodine receptor from skeletal muscle (RyR1). IpTx(a) is a peptide toxin that binds with h...

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Bibliographic Details
Main Authors: Samsó, Montserrat, Trujillo, Ramon, Gurrola, Georgina B., Valdivia, Hector H., Wagenknecht, Terence
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2156178/
https://ncbi.nlm.nih.gov/pubmed/10427100
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