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Activation of the Cdc42 Effector N-Wasp by the Shigella flexneri Icsa Protein Promotes Actin Nucleation by Arp2/3 Complex and Bacterial Actin-Based Motility

To propel itself in infected cells, the pathogen Shigella flexneri subverts the Cdc42-controlled machinery responsible for actin assembly during filopodia formation. Using a combination of bacterial motility assays in platelet extracts with Escherichia coli expressing the Shigella IcsA protein and i...

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Detalhes bibliográficos
Main Authors: Egile, Coumaran, Loisel, Thomas P., Laurent, Valérie, Li, Rong, Pantaloni, Dominique, Sansonetti, Philippe J., Carlier, Marie-France
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2156126/
https://ncbi.nlm.nih.gov/pubmed/10491394
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