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Identification of Shigella flexneri IcsA Residues Affecting Interaction with N-WASP, and Evidence for IcsA-IcsA Co-Operative Interaction

The Shigella flexneri IcsA (VirG) protein is a polarly distributed outer membrane protein that is a fundamental virulence factor which interacts with neural Wiskott-Aldrich syndrome protein (N-WASP). The activated N-WASP then activates the Arp2/3 complex which initiates de novo actin nucleation and...

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Detalhes bibliográficos
Main Authors: Teh, Min Yan, Morona, Renato
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566212/
https://ncbi.nlm.nih.gov/pubmed/23405119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055152
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