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Function of α3β1–Tetraspanin Protein Complexes in Tumor Cell Invasion. Evidence for the Role of the Complexes in Production of Matrix Metalloproteinase 2 (Mmp-2)

Tumor cell migration through the three- dimensional extracellular matrix (ECM) environment is an important part of the metastatic process. We have analyzed a role played by the integrin–tetraspanin protein complexes in invasive migration by culturing MDA-MB-231 cells within Matrigel. Using time-laps...

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Autori principali: Sugiura, Tsuyoshi, Berditchevski, Fedor
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2156113/
https://ncbi.nlm.nih.gov/pubmed/10491398
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