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Differential Processing of α- and β-Defensin Precursors by Matrix Metalloproteinase-7 (MMP-7)
Proteolytic processing of defensins is a critical mode of posttranslational regulation of peptide activity. Because mouse α-defensin precursors are cleaved and activated by matrix metalloproteinase-7 (MMP-7), we determined if additional defensin molecules, namely human neutrophil defensin pro-HNP-1...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2659188/ https://ncbi.nlm.nih.gov/pubmed/19181662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809744200 |
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