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Sickle cell vasoocclusion and rescue in a microfluidic device
The pathophysiology of sickle cell disease is complicated by the multiscale processes that link the molecular genotype to the organismal phenotype: hemoglobin polymerization occurring in milliseconds, microscopic cellular sickling in a few seconds or less [Eaton WA, Hofrichter J (1990) Adv Protein C...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2154459/ https://ncbi.nlm.nih.gov/pubmed/18077341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707122105 |
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