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MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression

MicroRNAs are single-stranded RNA of 18–24 nt expressed endogenously that play important roles in cancer development. Here, we show that expression of miR-378 enhances cell survival, reduces caspase-3 activity, and promotes tumor growth and angiogenesis. Proteomic analysis indicates reduced expressi...

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Détails bibliographiques
Auteurs principaux: Lee, Daniel Y., Deng, Zhaoqun, Wang, Chia-Hui, Yang, Burton B.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154434/
https://ncbi.nlm.nih.gov/pubmed/18077375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706901104
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