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The tumor suppressor Fhit acts as a repressor of β-catenin transcriptional activity
The Fra3B locus on chromosome 3p14.2 targeting the fragile histidine triad (Fhit) gene represents one of the most common fragile sites of the human genome and is associated with early preneoplastic and malignant disorders in multiple human tumors. Fhit was classified as a tumor suppressor; however,...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2154433/ https://ncbi.nlm.nih.gov/pubmed/18077326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703664105 |
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