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Sequence of late molecular events in the activation of rhodopsin

Activation of the G protein-coupled receptor rhodopsin involves both the motion of transmembrane helix 6 (TM6) and proton exchange events. To study how these activation steps relate to each other, spin-labeled rhodopsin in solutions of dodecyl maltoside was used so that time-resolved TM6 motion and...

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Détails bibliographiques
Auteurs principaux: Knierim, Bernhard, Hofmann, Klaus Peter, Ernst, Oliver P., Hubbell, Wayne L.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154424/
https://ncbi.nlm.nih.gov/pubmed/18077356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710393104
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