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Anatomical Differences and Atherosclerosis in Apolipoprotein E - Deficient Mice with 129/SvEv and C57BL/6 Genetic Backgrounds

There are well-known genetic background effects on atherosclerosis susceptibility in mice. To study the basis of these effects, we have generated the apolipoprotein E-null mutation in mouse embryonic stem cells of 129/SvEv origin, maintained it in the inbred strain (129-apoE), and compared these mic...

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Bibliografiske detaljer
Main Authors: Maeda, Nobuyo, Johnson, Lance, Kim, Shinja, Hagaman, John, Friedman, Morton, Reddick, Robert
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151972/
https://ncbi.nlm.nih.gov/pubmed/17275002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2006.12.006
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