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Differences in Aortic Arch Geometry, Hemodynamics, and Plaque Patterns between C57BL/6 and 129/SvEv Mice

Atherosclerotic plaques are distributed differently in the aortic arches of C57BL/6 (B6) and 129/SvEv (129) apolipoprotein E (apoE)- deficient mice. It is now recognized that hemodynamic shear stress plays an important role in the localization of atherosclerotic development. Since the blood flow fie...

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Bibliographic Details
Main Authors: Zhu, Hui, Zhang, Ji, Shih, Jessica, Long, David S., Lopez-Bertoni, Federico, Hagaman, John R., Maeda, Nobuyo, Friedman, Morton H.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047446/
https://ncbi.nlm.nih.gov/pubmed/20524728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1115/1.4000168
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