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Hyperoxia increases ventilator-induced lung injury via mitogen-activated protein kinases: a prospective, controlled animal experiment

INTRODUCTION: Large-tidal volume (V(T)) mechanical ventilation and hyperoxia used in patients with acute respiratory distress syndrome can damage pulmonary epithelial cells through lung inflammation and apoptotic cell death. Hyperoxia has been shown to increase ventilator-induced lung injury, but th...

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Detalhes bibliográficos
Main Authors: Li, Li-Fu, Liao, Shuen-Kuei, Ko, Yu-Shien, Lee, Cheng-Huei, Quinn, Deborah A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151853/
https://ncbi.nlm.nih.gov/pubmed/17316425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc5704
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