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Hyperoxia increases ventilator-induced lung injury via mitogen-activated protein kinases: a prospective, controlled animal experiment

INTRODUCTION: Large-tidal volume (V(T)) mechanical ventilation and hyperoxia used in patients with acute respiratory distress syndrome can damage pulmonary epithelial cells through lung inflammation and apoptotic cell death. Hyperoxia has been shown to increase ventilator-induced lung injury, but th...

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Bibliografiske detaljer
Main Authors: Li, Li-Fu, Liao, Shuen-Kuei, Ko, Yu-Shien, Lee, Cheng-Huei, Quinn, Deborah A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151853/
https://ncbi.nlm.nih.gov/pubmed/17316425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc5704
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