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Oct4 expression is not required for mouse somatic stem cell self-renewal

The Pou domain containing transcription factor Oct4 is a well-established regulator of pluripotency in the inner cell mass of the mammalian blastocyst as well as in embryonic stem cells. While it has been shown that the Oct4 gene is inactivated through a series of epigenetic modifications following...

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Detalhes bibliográficos
Main Authors: Lengner, Christopher J, Camargo, Fernando D, Hochedlinger, Konrad, Welstead, G Grant, Zaidi, Samir, Gokhale, Sumita, Scholer, Hans R, Tomilin, Alexey, Jaenisch, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151746/
https://ncbi.nlm.nih.gov/pubmed/18159219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2007.07.020
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