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Effects of Multiple Metal Binding Sites on Calcium and Magnesium-dependent Activation of BK Channels

BK channels are activated by physiological concentrations of intracellular Ca(2+) and Mg(2+) in a variety of cells. Previous studies have identified two sites important for high-affinity Ca(2+) sensing between [Ca(2+)](i) of 0.1–100 μM and a site important for Mg(2+) sensing between [Mg(2+)](i) of 0...

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Bibliografiske detaljer
Main Authors: Hu, Lei, Yang, Huanghe, Shi, Jingyi, Cui, Jianmin
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151482/
https://ncbi.nlm.nih.gov/pubmed/16344323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509317
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